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The Prevalence and Impact of 呼吸道合胞病毒(RSV)
在后COVID-19时代, there r教育津贴ins a heightened focus on respiratory diseases and what an RSV season will look like moving forward. We have learned, in particular, the importance of protecting those who are most vulnerable.
在婴儿和幼儿中, 呼吸道合胞病毒, 通常被称为RSV, 是最常见的呼吸道病毒之一吗.1,2 而呼吸道合胞病毒通常引起轻微, 冷若症状, it can progress to lower respiratory tract infections (LRTI), 如婴儿的细支气管炎和肺炎, making it a leading cause of hospitalisation in infants under 12 months.1-3
RSV每年在世界范围内引起季节性流行.4-6 While this virus is widespread, there r教育津贴ins no preventative option available for all infants.4-7 常见的卫生习惯，如勤洗手, 消毒表面和玩具, as well as avoiding close contact with people who are ill help prevent the spread of RSV.2
RSV可能是不可预测的.8 任何婴儿, 他们是否健康出生，是否足月出生, 过早的或有健康问题的, 能在第一个呼吸道合胞病毒季节住院吗.9,10 事实上, many hospitalisations occur in infants considered healthy and half of hospitalisations occur in older infants – those born before the start of the RSV season.9-12
RSV的几十年研究
尽管有60多年的研究, the scientific community has struggled to develop new preventative options in the RSV field.7 RSV prevention is limited to infants with preexisting conditions – leaving most infants unprotected from this virus.7,13
尽管有60多年的研究, the scientific community has struggled to develop new preventative options in the RSV field.7
对婴儿和家庭的影响
This virus is all too real for parents like Sanne van Barneveld, a mother who experienced RSV firsthand when her infant son Thijs, 谁是足月出生的, 在五周大的时候感染了病毒.
What started out as cold symptoms in Thijs eventually progressed, leading Sanne to take him to the paediatrician who then recommended he go to the hospital. 作为产科医生, 桑娜已经很熟悉呼吸道合胞病毒了, but to watch her young son fight the virus and eventually end up in the paediatric ICU was a painful experience.
在医院住了几天之后, Thijs was discharged and eventually made a full recovery; he is now a happy and healthy three-year-old. For Sanne, her advice to other parents is to know what the 呼吸道合胞病毒症状 are so they know what to watch for – and to seek medical attention when those symptoms become concerning.
致力于RSV预防的伙伴关系
No parent should have to witness their child struggle against this virus, and it’s up to us as a scientific community to strive to develop new solutions. Our partnership with Sanofi exemplifies the progress that can be made when collaboration is valued and fostered. 所有婴儿都需要预防呼吸道合胞病毒, and we are jointly committed to continuing our research and development to help HCPs improve care and management for this common and contagious respiratory illness.
参考文献。
1. 呼吸道合胞病毒(RSV). 疾病控制和预防中心. http://www.疾病预防控制中心.gov / rsv /索引.html. 2022年5月访问.
2. 呼吸 Syncytial Virus Infection (RSV): Infants and Young Children. 疾病控制和预防中心. http://www.疾病预防控制中心.gov / rsv /高风险/ infants-young-children.html. 2022年5月访问.
3. 领导人S, Kohlhase K. 呼吸 syncytial virus-coded 儿科 hospitalizations, 1997 to 1999. 儿科传染病杂志. 2002;21(7):629-32.
4. 皮埃迪蒙特G，佩雷斯MK. 呼吸 syncytial virus infection and bronchiolitis. Pediatr牧师. 2014;35:519-53.
5. 奥马尔·K等人. 婴幼儿急性细支气管炎的研究进展. 创伤复苏与急诊医学. 2014;22:23.
6. 史涛，等. 全球, 区域, and national disease burden estimates of acute lower respiratory infections due to 呼吸道合胞病毒 in young children in 2015: a syst教育津贴tic review and modelling study. Lancet 2017; 390: 946–58.
7. Villafana T，等. Passive and active immunization against 呼吸道合胞病毒 for the young and old. 专家Rev疫苗. 2017;16:1-39.
8. Bianchini S, Silvestri E, Argentiero A, Fainardi V, Pisi G, Esposito S. Role of 呼吸 Syncytial Virus in 儿科 Pneumonia. 微生物. 2020; 8(12):2048. http://doi.org/10.3390 / microorganisms8122048
9. Rha B等人. 呼吸 Syncytial Virus–Associated Hospitalizations among Young Children: 2015–2016. 儿科. 2020;146(1):e20193611.
10. Arriola CS, Kim L, Langley G, Anderson EJ, Openo K, Martin AM, 等. Estimated Burden of Community-Onset 呼吸 Syncytial Virus-Associated Hospitalizations Among Children Aged <2 Years in the United States, 2014-15. 儿科传染病学会杂志. 2020;9(5):587-95.
11. Reeves RM, Hardelid P, Panagiotopoulos N, Minaji M, Warburton F, Pebody R. Burden of hospital admissions caused by 呼吸道合胞病毒 (RSV) in infants in England: A data linkage modelling study. 感染杂志. 2019;78(6):468-75.
12. Demont C.纽约州佩特里卡市.巴杜拉，我. 等. Economic and disease burden of RSVassociated hospitalizations in young children in France, 2010年至2018年. BMC影响Dis 21,730 (2021). http://doi.org/10.1186/s12879-021-06399-8
13. Synagis - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. 可从:http://www获得.教育津贴.欧罗巴.eu/en/documents/product-information/synagis-epar-product-information_en.pdf 2022年5月访问.